Presbyopia literally means ‘old sight’. When we read or look at something close, the flexible lens inside the eye changes shape to provide the close focus required. However, as we age, the lens becomes less flexible and its ability to change shape is reduced.
- Presbyopia is a natural part of ageing and a gradual process that usually begins at around 40 years of age. As a result, almost everyone over the age of 45 needs vision correction for reading and other close work.
- Presbyopia is the most widespread ocular problem in the world. There are currently over 1 billion people with presbyopia.1
- In 2010, approximately 44% of the Australian population were in the presbyopic age bracket (almost 10 million people).1
- Presbyopia can be corrected with reading spectacles, bifocal or multifocal spectacles, and contact lenses.
These shortcomings are often exacerbated with low illumination levels. Such visual compromises have been associated with an increase in patient dropout rate and lack of confidence in fitting by practitioners.
We are currently developing a range of extended depth of focus (EDOF) contact lenses, which are designed to provide optimal visual performance from distance to near with minimal ghosting. The range of EDOF designs aim to deliver a vision solution for all presbyopes including emerging, early, medium and mature presbyopes.
Our EDOF contact lenses, using patented technology:
- use higher order aberrations to optimise retinal image quality over a wide range of distances from far to near while eliminating ghosting and haloes;
- perform relatively independent of patients natural aberrations and variation in pupil size; and
- are designed to meet the vision needs of emerging, moderate and advanced presbyopes.
We are now developing an IOL that incorporates EDOF principles to achieve good vision at all distances.
The Accommodating Gel is a clear gel-lens system that will replace the eye’s natural lens when it loses its ability to change power. The lens is removed during a procedure similar to that used for conventional cataract surgery and replaced by the polymer gel-lens. The major advantage of the Accommodating Gel technology is its unmatched ability to comfortably meet accommodation requirements for reading; ; providing correct focus at any distance just like the natural young lens.
The Accommodating Gel technology would be initially marketed as an alternative to conventional intraocular lens (IOL) replacement in cataract surgery procedures, wherein the opaque lens is removed and replaced by a synthetic IOL. The Accommodating Gel technology is available for co-development or licensing to commercial.
PublIc Health Strategies
In 2015, it was estimated that 1094 million people (mostly in developing communities) have inadequate correction for functional presbyopia.1 By quantifying the vast need for eye care services it provided evidence to support advocacy efforts with government and funding bodies, as well as planning for services.
In the same year, research by Brien Holden Vision Institute and partners, revealed the global economic cost in lost productivity due to uncorrected refractive error (URE) alone was a staggering US$202* billion each year2,3 (this did not include uncorrected presbyopia). It has since been estimated that a one-off investment of US$28 billion would be sufficient to establish and operate the educational and refractive care facilities required to deal with vision impairment resulting from URE.3
Such an investment would result in health, education, economic and quality of life benefits for individuals and a significant saving to the global economy.3
Find out more about our public health research.
*The original study estimated the loss in productivity in International Dollars. This was converted into U.S. Dollars in the subsequent study by Fricke and colleagues (2012).
This is largely due to a lack of facilities, infrastructure and the equipment necessary to provide eye care services, as well as a shortage of practitioners and other skilled personnel, especially in rural and remote areas in developing communities.
Our strategy to develop sustainable eye care services is based on the establishment of environments that enable trained eye care professional to provide much needed services locally.
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- Bourne et al, Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis. Lancet Glob Health. 2017 Sep;5(9):e888-e897.
- TST Smith, KD Frick, BA Holden, TR Fricke & KS Naidoo, Potential lost productivity resulting from the global burden of uncorrected refractive error, Bulletin of the World Health Organization 2009;87:431-437.
- Fricke TR, Holden BA, Wilson DA, Schlenther G, Naidoo KS, Resnikoff S & Frick KD. ‘Global cost of correcting vision impairment from uncorrected refractive error’, Bulletin of the World Health Organization, 2012; 90:728-738.
- Flaxman et al. Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis. Lancet Global Health. Published online October 11, 2017 http://dx.doi.org/10.1016/S2214-109X(17)30393-5